Synthetic Biology

Resolution of a human super-enhancer by targeted genome randomisation

Resolution of a human super-enhancer by target...

Synthetic Biology
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librarian
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A synthetic cell with integrated DNA self-replication and membrane biosynthesis

A synthetic cell with integrated DNA self-repl...

Synthetic Biology
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librarian
2 views
Development of FAP-targeted theranostics discovered by next-generation sequencing-augmented mining of a novel immunized VNAR library

Development of FAP-targeted theranostics disco...

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librarian
1 view
Life as a Function: Why Transformer Architectures Struggle to Gain Genome-Level Foundational Capabilities

Life as a Function: Why Transformer Architectu...

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Maximilian Sprange
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MiRNA Locker: A Modularized DNA Assembly As miRNA Inhibitors

MiRNA Locker: A Modularized DNA Assembly As mi...

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Xinyuan Qiu
2 views
Design of novel synthetic promoters to tune gene expression in T cells

Design of novel synthetic promoters to tune ge...

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Velia Siciliano
1 view
The Interplay Between Cell-cell Signaling and Negative Feedback Reduces Population Noise While Enhancing Single-cell Variability

The Interplay Between Cell-cell Signaling and ...

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librarian
1 view
Engineering of CRISPR-Cas PAM recognition using deep learning of vast evolutionary data

Engineering of CRISPR-Cas PAM recognition usin...

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librarian
36 views
Tissue-specific modulation of NADH consumption as an anti-aging intervention in Drosophila

Tissue-specific modulation of NADH consumption...

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Valentin Cracan
9 views
High-throughput protein binder discovery by rapid in vivo selection

High-throughput protein binder discovery by ra...

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librarian
3 views
Design of an exclusive obligate symbiosis for organism-based biological containment

Design of an exclusive obligate symbiosis for ...

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librarian
3 views
Engineered Living Glues for Autonomous Detection and On-Demand Treatment of Inflammatory Bowel Disease

Engineered Living Glues for Autonomous Detecti...

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Bolin An
7 views
Iterative acylation on mature lasso peptides by widespread acetyltransferases for lipolasso production

Iterative acylation on mature lasso peptides b...

Synthetic Biology
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librarian
5 views
A Linear Mixed Effects Model for Evaluating Synthetic Gene Circuits

A Linear Mixed Effects Model for Evaluating Sy...

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Hal Alper
7 views
Rewiring oncogenic signaling to RNA vector replication for the treatment of metastatic cancer

Rewiring oncogenic signaling to RNA vector rep...

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librarian
5 views
Direct RNA Oxford Nanopore sequencing distinguishes between modifications in tRNA at the U34 position

Direct RNA Oxford Nanopore sequencing distingu...

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librarian
8 views
A practical DNA data storage using expanded alphabet introducing 5-methylcytosine

A practical DNA data storage using expanded al...

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librarian
10 views
Accurate de novo design of a voltage-gated anion channel

Accurate de novo design of a voltage-gated ani...

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librarian
11 views
Virus-free continuous directed evolution in human cells using somatic hypermutation

Virus-free continuous directed evolution in hu...

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Angad Mehta
5 views
Multi-Step Pathway Engineering in Probiotic Saccharomyces boulardii for Abscisic Acid Production in the Gut

Multi-Step Pathway Engineering in Probiotic Sa...

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librarian
9 views
Design of multimodal antibiotics against intracellular infections using deep learning

Design of multimodal antibiotics against intra...

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librarian
5 views
In Vivo Pathway Optimization in Yeast via LoxPsym-Mediated Shuffling of Upstream Activating Sequences

In Vivo Pathway Optimization in Yeast via LoxP...

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Lena Hochrein
6 views
Termination sequence between an inducible promoter and ubiquitous chromatin opening element (UCOE) reduces gene expression leakage and silencing

Termination sequence between an inducible prom...

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librarian
9 views
GRN modeler: An Intuitive Tool for Constructing and Evaluating Gene Regulatory Networks and its Applications to Oscillators and a Light Biosensor

GRN modeler: An Intuitive Tool for Constructin...

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Ga´bor Hollo´
7 views
Silaffins-Driven Genetic Engineering of Diatom Cell Walls: Insight into Biosilica Morphology and Nanomaterial Design

Silaffins-Driven Genetic Engineering of Diatom...

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Baohua Zhu
9 views
StreptoCAD: An open-source software toolbox automating genome engineering workflows in streptomycetes

StreptoCAD: An open-source software toolbox au...

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librarian
6 views
Semantic mining of functional de novo genes from a genomic language model

Semantic mining of functional de novo genes fr...

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librarian
45 views
A Hot-Swappable Genetic Switch: Building an inducible and trackable functional assay for the essential gene MEDIATOR 21

A Hot-Swappable Genetic Switch: Building an in...

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librarian
7 views
Combined biosynthesis and site-specific incorporation of phenylalanine derivatives from aryl aldehydes or carboxylic acids in engineered bacteria

Combined biosynthesis and site-specific incorp...

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librarian
7 views
A protein cage system for producing bioactive peptides in Escherichia coli

A protein cage system for producing bioactive ...

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Nicole Lawrence
11 views
Mapping targetable sites on the human surfaceome for the design of novel binders

Mapping targetable sites on the human surfaceo...

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librarian
32 views
A Conditional Degron Tag for RNA Sensing in Bacteria

A Conditional Degron Tag for RNA Sensing in Ba...

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Ming Hammond
7 views
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