Synthetic Biology

Humanized Caffeine-Inducible Systems for Controlling Cellular Functions
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Leo Scheller
24 views
Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosis
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librarian
25 views
Caffeine-regulated molecular switches for functional control of CAR T cells in vivo
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librarian
20 views
Treating Myotonic Dystrophy with artificial RNA endonucleases to specifically degrade toxic RNA expansions
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librarian
24 views
Phage-Assisted Evolution of Allosteric Protein Switches
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librarian
35 views
Heterologous expression of microbial nitroreductases for TNT degradation in transgenic animals
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librarian
44 views
A DNA part library for reliable engineering of the emerging model nematode symbiotic bacterium Xenorhabdus griffiniae HGB2511
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Elin Larsson
56 views
Engineering lung-sensing T cells using synthetic receptors targeting RAGE
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librarian
77 views
Single-cell characterization of bacterial optogenetic Cre recombinases
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librarian
77 views
Tuning viscoelasticity and fine structure of living materials via synthetic adhesion logic and rheological perturbations
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librarian
97 views
Cell-free genome-wide transcriptomics through machine learning optimization
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librarian
96 views
DNA framework array enables ultra-high throughput DNA synthesis
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librarian
116 views
Unified Genomic and Chemical Representations Enable Bidirectional Bio-synthetic Gene Cluster and Natural Product Retrieval
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Chuan Sheng Foo
120 views
Carbon-Efficient Conversion through Hydrogen and Formate-Driven Metabolism in Escherichia coli
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Jay Keasling
120 views
DNA Flipping as Facile Mechanism for Transmembrane Signaling in Synthetic Cells
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Lorena Pellejero
120 views
Changing the initiation unit of nonribosomal peptide synthetases to access underexplored biosynthetic potential
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Xiaoying Bian
119 views
De novo design of hundreds of functional GPCR-targeting antibodies enabled by scaling test-time compute
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librarian
120 views
Making deep mutational scanning accessible: a cost-efficient approach to construct barcoded libraries for genes of any length
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librarian
120 views
Characterization of recombinase-based genetic parts and circuits using nanopore sequencing
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librarian
121 views
Using domain insertion to create sulfite reductases that present chemical-dependent activities
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librarian
120 views
Orchestrating Self-Replication in Artificial Cells through Digital Microfluidics
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Mark Wallace
121 views
When good guides go bad: empirical evaluation of all unique Cas9 targets in E. coli reveal widespread functionality and rules for gRNA biological design
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librarian
121 views
Combinatorial mutagenesis of N-terminal sequences reveals unexpected and expanded stability determinants of the Escherichia coli N-degron pathway
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librarian
121 views
Peptide Barcodes for miRNA activity assessment in mammalian cells
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librarian
122 views
Integration of strain and process optimization to increase autotrophic growth of engineered Komagataella phaffii
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librarian
121 views
Unveiling the hidden window of prime editing
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librarian
123 views
PYEAST - Python Enabled Automated Strain Transformaiton
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Carol Hartley
125 views
Multiobjective learning and design of bacteriophage specificity
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librarian
124 views
Experimental Evaluation of AI-Driven Protein Design Risks Using Safe Biological Proxies
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Geoffrey Taghon
133 views
Engineered Acinetobacter baylyi ADP1-ISx cells are sensitive DNA biosensors for antibiotic resistance genes and a fungal pathogen of bats
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librarian
125 views
Sequestration-Based Neural Networks That Operate Out of Equilibrium
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librarian
127 views
A Saccharomyces boulardii synthetic biotic platform for delivery of therapeutic nanobodies to ameliorate gastrointestinal inflammation
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librarian
133 views