Pharmacology and Toxicology

Decoding Cellular Stress States for Toxicology Using Single-Cell Transcriptomics

Decoding Cellular Stress States for Toxicology...

Pharmacology and Toxicology
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librarian
25 views
Metadimensional simulation for biochemistry and pharmacology learning

Metadimensional simulation for biochemistry an...

Pharmacology and Toxicology
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Thomaz Rocha e Silva
45 views
Evaluation of graphene oxide-mediated NET formation using HL-60-derived neutrophil-like cells

Evaluation of graphene oxide-mediated NET form...

Pharmacology and Toxicology
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Kiyoshi Fukuhara
66 views
Simpatico: accurate and ultra-fast virtual drug screening with atomic embeddings

Simpatico: accurate and ultra-fast virtual dru...

Pharmacology and Toxicology
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Jeremiah Gaiser
65 views
Stereospecific rapid activation of Transcription Factor EB (TFEB) by Levacetylleucine (NALL)

Stereospecific rapid activation of Transcripti...

Pharmacology and Toxicology
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Antony Galione
65 views
Contrastive learning of adverse events to provide effective and interpretable vector representations for machine-assisted pharmacovigilance

Contrastive learning of adverse events to prov...

Pharmacology and Toxicology
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librarian
65 views
Inhibiting RhoA Activation via GDP-state Stabilization to Relieve Heart Failure

Inhibiting RhoA Activation via GDP-state Stabi...

Pharmacology and Toxicology
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Yong Wang
83 views
SLAB: Simultaneous Labeling And Binding affinity prediction for protein-ligand structures

SLAB: Simultaneous Labeling And Binding affini...

Pharmacology and Toxicology
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librarian
89 views
TREM2 Hit Discovery Using TRIC Technology: A Proof-of-Concept High-Throughput Screening Approach

TREM2 Hit Discovery Using TRIC Technology: A P...

Pharmacology and Toxicology
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librarian
90 views
Evolving resistance patterns in Tetranychus urticae and Bemisia tabaci in Greece

Evolving resistance patterns in Tetranychus ur...

Pharmacology and Toxicology
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librarian
103 views
Determination of chemical partitioning in vehicles using a skin surrogate for dermal absorption model refinement.

Determination of chemical partitioning in vehi...

Pharmacology and Toxicology
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librarian
116 views
Stochastic gates for covariate selection in population pharmacokinetics modelling

Stochastic gates for covariate selection in po...

Pharmacology and Toxicology
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librarian
110 views
Rules of engagement: determinants of chemokine receptor activation and selectivity by CCL27 and CCL28

Rules of engagement: determinants of chemokine...

Pharmacology and Toxicology
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librarian
114 views
Oxidative stress and vacuolar variants influence paraquat response in Saccharomyces cerevisiae of different genetic variants

Oxidative stress and vacuolar variants influen...

Pharmacology and Toxicology
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Andres Klein
115 views
IQM-22110 as a selective KV4.3/KChIP3 modulator. Molecular determinants of the KChIP3 binding site

IQM-22110 as a selective KV4.3/KChIP3 modulato...

Pharmacology and Toxicology
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librarian
118 views
Non-Equilibrium Snapshots of Ligand Efficacy at the μ-Opioid Receptor

Non-Equilibrium Snapshots of Ligand Efficacy a...

Pharmacology and Toxicology
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Georgios Skiniotis
115 views
Validation of a high-throughput screening assay for the characterization of cryoprotective agent toxicity

Validation of a high-throughput screening assa...

Pharmacology and Toxicology
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Rebecca Sandlin
114 views
Discovery and Development of DC-174 as a Novel Oral Snakebite Treatment

Discovery and Development of DC-174 as a Novel...

Pharmacology and Toxicology
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librarian
117 views
In-dwelling microfluidic device for precise and reliable intranasal drug delivery during freely-moving behavior

In-dwelling microfluidic device for precise an...

Pharmacology and Toxicology
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librarian
116 views
TRPV4 activation enhances LPS-induced IL10 production to suppress excessive microglial activation

TRPV4 activation enhances LPS-induced IL10 pro...

Pharmacology and Toxicology
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librarian
117 views
Mechanism of SK2 channel gating and its modulation by the bee toxin apamin and small molecules

Mechanism of SK2 channel gating and its modula...

Pharmacology and Toxicology
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librarian
116 views
Neurotoxicity of Propylene Glycol Butyl Ether: Multiomic Evidence from Human BrainSpheres

Neurotoxicity of Propylene Glycol Butyl Ether:...

Pharmacology and Toxicology
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Marie-Gabrielle Zurich
161 views
Endothelial c-IAP2 Loss Amplifies P2X7 Receptor-Driven Inflammation and Worsens Infection-Associated Pulmonary Hypertension

Endothelial c-IAP2 Loss Amplifies P2X7 Recepto...

Pharmacology and Toxicology
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Suellen Oliveira
115 views
Identification of antibody-drug conjugate payloads which are substrates of ATP-binding cassette drug efflux transporters

Identification of antibody-drug conjugate payl...

Pharmacology and Toxicology
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Matthew Hall
116 views
Identification of new KCNT1-epilepsy drugs by in silico, cell and Drosophila modelling.

Identification of new KCNT1-epilepsy drugs by ...

Pharmacology and Toxicology
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Jonathan Lippiat
131 views
Intranasal Dantrolene Nanoparticles for Treatment of Amyotrophic Lateral Sclerosis as a Disease-Modifying Drug

Intranasal Dantrolene Nanoparticles for Treatm...

Pharmacology and Toxicology
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librarian
115 views
Bisdemethoxycurcumin mitigates Alzheimer disease pathology through autophagy-mediated reduction of senescence and amyloid beta

Bisdemethoxycurcumin mitigates Alzheimer disea...

Pharmacology and Toxicology
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Ajay Kumar
124 views
Evaluating the efficacy of LUMPY-NIL herbal powder, dermal Spray and dermal ointment in treating Lumpy Skin Disease (LSD) in Bovines

Evaluating the efficacy of LUMPY-NIL herbal po...

Pharmacology and Toxicology
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librarian
119 views
RAC1 Regulates Shh-Medulloblastoma Growth via GLI-Mediated Transcription

RAC1 Regulates Shh-Medulloblastoma Growth via ...

Pharmacology and Toxicology
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librarian
116 views
Alcohol Disrupts Neural Differentiation Through Endoplasmic Reticulum Stress and PERK Pathway Activation

Alcohol Disrupts Neural Differentiation Throug...

Pharmacology and Toxicology
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librarian
119 views
Mitragynine and 7-Hydroxymitragynine: Bidirectional Effects on Breathing in Rats

Mitragynine and 7-Hydroxymitragynine: Bidirect...

Pharmacology and Toxicology
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Samuel Obeng
121 views
Differential responses of murine embryonic stem cells (mESC) and their endothelial progeny to doxorubicin and pharmacological inhibitors of DNA repair and DNA damage response

Differential responses of murine embryonic ste...

Pharmacology and Toxicology
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librarian
118 views
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