Immunology

Rational Generation of Monoclonal Antibodies and Intrabodies Selective for Pathogenic TDP-43

Rational Generation of Monoclonal Antibodies a...

Immunology
Avatar
librarian
13 views
Mitochondrial Bioenergetic Failure in SLE Immunocytes: Targeting Fitness for Therapy

Mitochondrial Bioenergetic Failure in SLE Immu...

Immunology
Avatar
librarian
11 views
Accumulation of SA-βGal High Cells in Human Naive T Cell Compartments Reveals a Stress-Adapted, Senescent-Like State

Accumulation of SA-βGal High Cells in Human Na...

Immunology
Avatar
librarian
12 views
A single MHCII neoepitope mRNA vaccine elicits CD4 T- and B- cell responses promoting endogenous CD8 anti-tumor immunity

A single MHCII neoepitope mRNA vaccine elicits...

Immunology
Avatar
Aude-Hélène Capietto
38 views
Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis

Depletion of extracellular asparagine impairs ...

Immunology
Avatar
librarian
44 views
Selective targeting of IL-1RAP-dependent eosinophilic inflammation in allergic fungal airway disease

Selective targeting of IL-1RAP-dependent eosin...

Immunology
Avatar
librarian
45 views
Measles vaccine attenuation comprises innate immune cell infection and interferon responses

Measles vaccine attenuation comprises innate i...

Immunology
Avatar
Christian Pfaller
47 views
ALOX12B overexpression in the skin drives inflammasome/Th17 signaling axis to promote inflammation in the mouse model and human patients

ALOX12B overexpression in the skin drives infl...

Immunology
Avatar
Nooruddin Khan
46 views
DEVELOPMENT OF A POTENT MONOCLONAL ANTIBODY FOR TREATMENT OF HUMAN METAPNEUMOVIRUS INFECTIONS

DEVELOPMENT OF A POTENT MONOCLONAL ANTIBODY FO...

Immunology
Avatar
Jim Boonyaratanakornkit
67 views
How Ikaros and Aiolos homo- and heterodimers drive gene expression to ensure B cell development

How Ikaros and Aiolos homo- and heterodimers d...

Immunology
Avatar
Susan Chan
50 views
Dendritic cell-intrinsic TLR/MyD88 signaling promotes the clearance of a live-attenuated oral vaccine

Dendritic cell-intrinsic TLR/MyD88 signaling p...

Immunology
Avatar
Guangming Zhong
46 views
Kmo restricts Salmonella in a whole organism infection model by promoting macrophage lysosomal acidification through kainate receptor antagonism.

Kmo restricts Salmonella in a whole organism i...

Immunology
Avatar
librarian
46 views
Impact of serum versus anticoagulant-containing plasma on influenza virusneuraminidase-based serological assays

Impact of serum versus anticoagulant-containin...

Immunology
Avatar
librarian
45 views
Loss of B cell tolerance at the T2/T3a B cell transition is a convergent pathogenic mechanism in common variable immunodeficiency

Loss of B cell tolerance at the T2/T3a B cell ...

Immunology
Avatar
Jocelyn Farmer
46 views
Maintenance of chronic neuroinflammation in multiple sclerosis via interferon signaling and CD8 T cell-mediated cytotoxicity

Maintenance of chronic neuroinflammation in mu...

Immunology
Avatar
librarian
53 views
The immune landscape of pediatric Brain and Solid Tumors: A systematic review and integration of immunohistochemistry and single-cell RNA sequencing data

The immune landscape of pediatric Brain and So...

Immunology
Avatar
librarian
58 views
Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

Acute anaphylactic and multiorgan inflammatory...

Immunology
Avatar
librarian
60 views
Zα domain-dependent ZBP1 condensate formation induces an amyloidal necroptotic signalling complex

Zα domain-dependent ZBP1 condensate formation ...

Immunology
Avatar
librarian
63 views
Inflammasome activation differences underpin different Mycobacterium tuberculosis infection outcomes

Inflammasome activation differences underpin d...

Immunology
Avatar
librarian
68 views
Imaging CRISPR-Edited CAR-T Cell Therapies with Optical and Positron Emission Tomography Reporters

Imaging CRISPR-Edited CAR-T Cell Therapies wit...

Immunology
Avatar
librarian
65 views
Persistent ECM Scarring Reprograms Intestinal Stem Cells to Drive Chronic Inflammation

Persistent ECM Scarring Reprograms Intestinal ...

Immunology
Avatar
librarian
73 views
TH5487 specifically targets NLRP3 in FCAS patients resistant to MCC950

TH5487 specifically targets NLRP3 in FCAS pati...

Immunology
Avatar
librarian
71 views
Interlinked roles for HEB and Id3 in fetal gamma-delta T cell commitment and functional programming

Interlinked roles for HEB and Id3 in fetal gam...

Immunology
Avatar
librarian
74 views
CFTR mutation leads to intrinsic dysfunction in neutrophils from people with Cystic Fibrosis

CFTR mutation leads to intrinsic dysfunction i...

Immunology
Avatar
Santiago PartidaSanchez
69 views
Duration of immunity following infection with moderately virulent ASFV

Duration of immunity following infection with ...

Immunology
Avatar
librarian
69 views
Rational Design of Immunogenic Nanoparticles as a Platform for Enhanced Ovarian Cancer Immunotherapy in Mice

Rational Design of Immunogenic Nanoparticles a...

Immunology
Avatar
librarian
70 views
Clusterin reverses epitheliopathy, reduces inflammation, and restores goblet cells and corneal nerves in a mouse model of autoimmune dry eye

Clusterin reverses epitheliopathy, reduces inf...

Immunology
Avatar
librarian
70 views
Unheralded high MHC Class II polymorphism in the abundant Atlantic herring resolved by long-read sequencing

Unheralded high MHC Class II polymorphism in t...

Immunology
Avatar
librarian
71 views
Transcriptome-Proteome analysis of human naive and memory B cell subsets reveal isotype and subclass-specific phenotypes

Transcriptome-Proteome analysis of human naive...

Immunology
Avatar
librarian
70 views
Single-cell and cell-type-level insights into stress-driven immune regulation relevant to disease

Single-cell and cell-type-level insights into ...

Immunology
Avatar
Anthony Zannas
73 views
KDM5A enhances MHC-I antigen presentation and potentiates antitumor immunity unleashed by immune checkpoint blockade

KDM5A enhances MHC-I antigen presentation and ...

Immunology
Avatar
librarian
74 views
Locust cGAS-like receptors recognize derivatives of a Gypsy retrotransposon to synergize with RNAi against viral invasion

Locust cGAS-like receptors recognize derivativ...

Immunology
Avatar
He-Ying Qian
70 views
Load more