Cancer Biology

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and Tamoxifen in a luminal A breast cancer model

PAK1 activation drives divergent resistance me...

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librarian
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Comparative Analysis of the Effects of PSPH and PHGDH Inhibitors on Tumor Cell Proliferation

Comparative Analysis of the Effects of PSPH an...

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librarian
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Tumor-specific draining lymph node CD8 T cells orchestrate an anti-tumor response to neoadjuvant PD-1 immune checkpoint blockade

Tumor-specific draining lymph node CD8 T cells...

Cancer Biology
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Jonathan Villena-Vargas
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Dexamethasone-Induced p57-Mediated Quiescence Drives Chemotherapy Resistance in Sonic Hedgehog Medulloblastoma

Dexamethasone-Induced p57-Mediated Quiescence ...

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James Purzner
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CISH, a novel intracellular immune checkpoint, in comparison and combination to existing and emerging cancer immune checkpoints

CISH, a novel intracellular immune checkpoint,...

Cancer Biology
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Tom Henley
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Plasma protein biomarkers for the early detection of gastric preneoplasia and cancer: a prospective study

Plasma protein biomarkers for the early detect...

Cancer Biology
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Eliette Touati
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SNX-2112 inhibits the ERBB3high tumor population in Plexiform Neurofibromas

SNX-2112 inhibits the ERBB3high tumor populati...

Cancer Biology
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librarian
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NOTCH1 Acts as a Tumor Suppressor That Induces Early Differentiation in Head and Neck Cancer

NOTCH1 Acts as a Tumor Suppressor That Induces...

Cancer Biology
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librarian
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Distinct druggable biological processes in early-onset prostate cancer

Distinct druggable biological processes in ear...

Cancer Biology
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Bissan Al-Lazikani
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Exploiting the CXCR3/CXCL10 pathway to override tumor immune suppression by enhancing immune trafficking and effector cell priming in head and neck squamous cell carcinoma

Exploiting the CXCR3/CXCL10 pathway to overrid...

Cancer Biology
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librarian
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Multi-cellular phenotypic dynamics during the progression of breast tumors

Multi-cellular phenotypic dynamics during the ...

Cancer Biology
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Jean Hausser
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Single-cell transcriptomic analysis of HPV-related multiphenotypic sinonasal carcinoma uncovers MYB-HPV association

Single-cell transcriptomic analysis of HPV-rel...

Cancer Biology
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librarian
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Specific degrader for fusion oncokinase kills tumors and is augmented by bimodal degrader-siRNA

Specific degrader for fusion oncokinase kills ...

Cancer Biology
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Mahsa Shirani
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Identification of Raptor and GLI1 as USP37 substrates highlight its context-specific function in medulloblastoma cells.

Identification of Raptor and GLI1 as USP37 sub...

Cancer Biology
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librarian
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A microRNA-based Therapy against Human Medulloblastoma Validated in a Xenotransplant Model using Wild-Type Mouse Embryos

A microRNA-based Therapy against Human Medullo...

Cancer Biology
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Davide De Pietri Tonelli
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Mechanisms of resistance to active state selective tri-complex RAS inhibitors

Mechanisms of resistance to active state selec...

Cancer Biology
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Piro Lito
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Longitudinal single-cell RNA sequencing of a neuroendocrine transdifferentiation model reveals transcriptional reprogramming in treatment-induced neuroendocrine prostate cancer

Longitudinal single-cell RNA sequencing of a n...

Cancer Biology
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Colin Collins
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Adipocytes in tumour microenvironment promote chemoresistance in TNBC through oxysterols

Adipocytes in tumour microenvironment promote ...

Cancer Biology
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Giorgia Cioccoloni
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Pancreatic cancer patient-derived organoids capture therapy response and tumor evolution

Pancreatic cancer patient-derived organoids ca...

Cancer Biology
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librarian
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Glutamine transporters regulate prostate cancer radiosensitivity through NUPR1-mediated stress response

Glutamine transporters regulate prostate cance...

Cancer Biology
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Anna Dubrovska
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A nuclear branched-chain amino acid catabolism pathway controls histone propionylation in pancreatic cancer

A nuclear branched-chain amino acid catabolism...

Cancer Biology
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Nathaniel Snyder
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Oncogene SETDB1s Dual Role in Endometrial Cancer: Driving Tumor Progression and Immune Escape

Oncogene SETDB1s Dual Role in Endometrial Canc...

Cancer Biology
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Shujie Yang
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Interrupting Elmsan1 repression of nuclear Acetyl-CoA production therapeutically reprograms cancer cells

Interrupting Elmsan1 repression of nuclear Ace...

Cancer Biology
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librarian
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CASTOR1: A Novel Tumor Suppressor Linking mTORC1 and KRAS Pathways in Tumorigenesis and Resistance to KRAS-Targeted Therapies in Non-Small Cell Lung Cancer

CASTOR1: A Novel Tumor Suppressor Linking mTOR...

Cancer Biology
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librarian
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The anti-metabolite KAT/3BP has in vitro and in vivo anti-tumor activity in lymphoma models

The anti-metabolite KAT/3BP has in vitro and i...

Cancer Biology
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librarian
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TIGIT expression dictates the immunosuppressive reprogramming of myeloid cells in glioblastoma

TIGIT expression dictates the immunosuppressiv...

Cancer Biology
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Benjamin Himes
6 views
Repurposing Quetiapine as an Adjuvant Therapeutic Agent for Triple-Negative Breast Cancer

Repurposing Quetiapine as an Adjuvant Therapeu...

Cancer Biology
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Ling He
8 views
A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter SLC43A1 (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cells

A whole genomic CRISPR-Cas9 screen identifies ...

Cancer Biology
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librarian
4 views
Cell state transitions drive the evolution of disease progression in B-lymphoblastic leukemia

Cell state transitions drive the evolution of ...

Cancer Biology
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librarian
4 views
Inter-Spheroid Proximity and Matrix Remodeling Determine CAF-Mediated Cancer Cell Invasion

Inter-Spheroid Proximity and Matrix Remodeling...

Cancer Biology
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librarian
4 views
2H MRI-based quantification of leucine uptake in glioblastoma multiforme

2H MRI-based quantification of leucine uptake ...

Cancer Biology
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Scott Beeman
8 views
BRCA2 reversion mutation-independent resistance to PARP inhibition in prostate cancer through loss of function perturbations in the DNA pre-replication complex

BRCA2 reversion mutation-independent resistanc...

Cancer Biology
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librarian
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