Cancer Biology

Spatial analysis reveals a novel inflammatory tumor transition state which promotes a macrophage-driven induction of sarcomatoid renal cell carcinoma

Spatial analysis reveals a novel inflammatory ...

Cancer Biology
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librarian
11 views
Cancer systems immunology reveals myeloid - T cell interactions and B cell activation mediate response to checkpoint inhibition in metastatic breast cancer

Cancer systems immunology reveals myeloid - T ...

Cancer Biology
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librarian
21 views
Spatial multi-omics and deep learning reveal fingerprints of immunotherapy response and resistance in hepatocellular carcinoma

Spatial multi-omics and deep learning reveal f...

Cancer Biology
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Alexandro Trevino
24 views
Expression of β-catenin, LEF-1, MMP7 and SFRP5 associated with poor outcome in pancreatic cancer

Expression of β-catenin, LEF-1, MMP7 and SFRP5...

Cancer Biology
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librarian
29 views
Targeted inhibition of colorectal carcinoma using a designed CEA-binding protein to deliver TCF/LEF transcription factor decoy DNA and p53 protein

Targeted inhibition of colorectal carcinoma us...

Cancer Biology
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Geng Wu
30 views
Lycopene Suppresses Lung Cancer Progression via PI3K/AKT Pathway Inhibition and Apoptosis Induction: Mechanistic and Safety Insights from Preclinical Models

Lycopene Suppresses Lung Cancer Progression vi...

Cancer Biology
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Xianting Yan
42 views
Human fibrosarcoma cells selected for very-high doxorubicin resistance, acquire trabectedin and eribulin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression

Human fibrosarcoma cells selected for very-hig...

Cancer Biology
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librarian
39 views
FRA1 drives melanoma metastasis through an actionable transcriptional network

FRA1 drives melanoma metastasis through an act...

Cancer Biology
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librarian
54 views
Brain FGF2 and NCAM1 contribute to FGFR1-dependent progression of ER+ breast cancer brain metastases in young and aged hosts

Brain FGF2 and NCAM1 contribute to FGFR1-depen...

Cancer Biology
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librarian
60 views
Infrared Laser Sampling of Low Volumes Reveals Marker Lipids in Palatine Tonsil Carcinoma via Shotgun Lipidomics

Infrared Laser Sampling of Low Volumes Reveals...

Cancer Biology
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librarian
68 views
Identification and Validation of a Previously Missed Mutational Signature in Colorectal Cancer

Identification and Validation of a Previously ...

Cancer Biology
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librarian
65 views
Extracellular vesicle-derived miR-425-5p (miR-425) activates astrocytes in the brain to promote breast cancer brain metastasis via the novel miR-425-ZNF24-CCL8 signaling axis

Extracellular vesicle-derived miR-425-5p (miR-...

Cancer Biology
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librarian
63 views
Intra-subtype heterogeneity shapes treatment response in KMT2A-rearranged ALL across all age groups

Intra-subtype heterogeneity shapes treatment r...

Cancer Biology
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librarian
67 views
Single JAK2-V617F hematopoietic stem cells can initiate MPN in transplantations into non-conditioned recipient mice

Single JAK2-V617F hematopoietic stem cells can...

Cancer Biology
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librarian
65 views
HNF4α controls growth, identity and response to KRAS inhibition of invasive mucinous adenocarcinoma of the lung

HNF4α controls growth, identity and response t...

Cancer Biology
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librarian
84 views
Development of a liposomal formulation of a TKI: the active loading of erlotinib.HCl

Development of a liposomal formulation of a TK...

Cancer Biology
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librarian
84 views
Paracrine Signals from HIV-1 Infected Immune Cells Reprogram Cervical Cancer Pathways

Paracrine Signals from HIV-1 Infected Immune C...

Cancer Biology
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Mehdi Bouhaddou
84 views
METTL5 Blockade Enhances Anti-Tumor Immune Response via Inducing Neoantigen Generation

METTL5 Blockade Enhances Anti-Tumor Immune Res...

Cancer Biology
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Hao Chen
85 views
Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia via a cytotoxic integrated stress response

Acid ceramidase inhibition enhances BCL-2 targ...

Cancer Biology
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librarian
85 views
Dietary lipids, not ketone body metabolites, influence intestinal tumorigenesis in a ketogenic diet

Dietary lipids, not ketone body metabolites, i...

Cancer Biology
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Ömer Yilmaz
85 views
Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis

Pancreatic cancer cachexia is mediated by PTHr...

Cancer Biology
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librarian
87 views
Integrative analysis of mRNA stability regulation uncovers a metastasis-suppressive program in breast cancer

Integrative analysis of mRNA stability regulat...

Cancer Biology
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librarian
85 views
TRPV4 Channels Mediate Bladder Cancer Cell Proliferation, Migration and Chemoresistance

TRPV4 Channels Mediate Bladder Cancer Cell Pro...

Cancer Biology
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librarian
83 views
Modeling acquired TKI resistance and effective combination therapeutic strategies in murine RET+ lung adenocarcinoma

Modeling acquired TKI resistance and effective...

Cancer Biology
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Lynn Heasley
83 views
Optimising Chemotherapy for Locally Advanced High-Grade Serous Ovarian Cancer via Delay-Differential Equations

Optimising Chemotherapy for Locally Advanced H...

Cancer Biology
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librarian
83 views
Dual inhibition of EGFR and PI3Kinase signaling in EGFR amplified triple negative breast cancer cells induces apoptosis and reduces tumor growth

Dual inhibition of EGFR and PI3Kinase signalin...

Cancer Biology
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librarian
83 views
Live-cell analyses with unsegmented images to study cancer cell response to modified T cell therapy

Live-cell analyses with unsegmented images to ...

Cancer Biology
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librarian
84 views
Tumor-Educated-Platelets interact with Breast Cancer-Stem-Cells via P-selectin- PSGL1 and ensure stemness and metastasis through WNT-β-Catenin-VEGF-VEGFR2 intra-cellular signaling: Therapeutic modulation by aspirin

Tumor-Educated-Platelets interact with Breast ...

Cancer Biology
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librarian
84 views
Integrative Transcriptomic and miRNA Analysis Reveals Immune Suppression and Metabolic Reprogramming in FGFR3-TACC3 Fusion-Positive versus Fusion-Negative Bladder Cancer

Integrative Transcriptomic and miRNA Analysis ...

Cancer Biology
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librarian
85 views
LSH-mediated resolution of R-loops mitigates transcription-replication conflicts to preserve genomic stability in prostate cancer cells

LSH-mediated resolution of R-loops mitigates t...

Cancer Biology
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Kai Ni
88 views
A multi-step immune-competent genetic mouse model reveals phenotypic plasticity in uveal melanoma

A multi-step immune-competent genetic mouse mo...

Cancer Biology
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Xiaonan Xu
85 views
TATA box-based analysis reveals activation of growth programs in bladder cancer cells despite ferroptosis activation

TATA box-based analysis reveals activation of ...

Cancer Biology
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librarian
82 views
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