Cancer Biology

Co-evolution of Oncogenic KRAS Signaling and LILRBhigh Macrophages Drives Pancreatic Cancer Recurrence

Co-evolution of Oncogenic KRAS Signaling and L...

Cancer Biology
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Li Wen
3 views
Single-Cell Transcriptomic Signatures Enable Stratified Combination Therapy for Platinum-Resistant Ovarian Cancer

Single-Cell Transcriptomic Signatures Enable S...

Cancer Biology
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librarian
2 views
Engineered subtilisin protease degrades active KRAS in cancer cells, leading to differential cell targeting

Engineered subtilisin protease degrades active...

Cancer Biology
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librarian
2 views
Patient-derived organoids from malignant pleural effusion to explore for alternative therapies in thoracic tumors

Patient-derived organoids from malignant pleur...

Cancer Biology
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Luis Leon-Mateos
3 views
A guide for establishing patient-derived organoids from bile samples obtained during endoscopic procedures and performing gene expression knockdown

A guide for establishing patient-derived organ...

Cancer Biology
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Maria Arechederra
3 views
Metabolic reprogramming controlled by NF-YA alternative splicing creates therapeutic opportunities in colorectal cancer

Metabolic reprogramming controlled by NF-YA al...

Cancer Biology
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Carol Imbriano
9 views
Neuroepithelial reprogramming and ERBB vulnerability in canine acanthomatous ameloblastoma

Neuroepithelial reprogramming and ERBB vulnera...

Cancer Biology
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Praveen Sethupathy
4 views
Single-Cell Cross-Species Profiling identifies Conserved Transcriptional Networks in Early Pancreatic Tumourigenesis.

Single-Cell Cross-Species Profiling identifies...

Cancer Biology
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librarian
6 views
Hormone signaling and immune programs define differential endocrine responsiveness in high-risk breast tissue

Hormone signaling and immune programs define d...

Cancer Biology
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Jennifer Rosenbluth
4 views
A bivalent lysine-acetylated small-molecule binding site in MYC

A bivalent lysine-acetylated small-molecule bi...

Cancer Biology
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Sarki Abdulkadir
5 views
Targeting CPSF73, the mRNA 3' End Processing Endonuclease, Moves Cancer Cells Away from the Mesenchymal State

Targeting CPSF73, the mRNA 3' End Processing E...

Cancer Biology
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Claire Moore
4 views
Replication competent adenoviral platform for in situ production of immunotherapeutic RNA aptamers targeting 4 1BB

Replication competent adenoviral platform for ...

Cancer Biology
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Fernando Pastor
7 views
Suppression of early pro-inflammatory senescent signature post-radiotherapy mitigates chronic bone damage

Suppression of early pro-inflammatory senescen...

Cancer Biology
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librarian
4 views
Mechanotranscriptomic Profiling of Breast Cancer Cells Intravasated from Engineered Microtumors

Mechanotranscriptomic Profiling of Breast Canc...

Cancer Biology
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librarian
4 views
Transcriptomic profiling of mouse mammary tumors enables prognostic and predictive biomarker discovery for human breast cancers

Transcriptomic profiling of mouse mammary tumo...

Cancer Biology
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Charles Perou
9 views
Single cell Correlation Analysis (SCA): Identifying self-renewing subpopulation of human acute myeloid leukemia stem cells using single cell RNA sequencing analysis

Single cell Correlation Analysis (SCA): Identi...

Cancer Biology
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Zohar Sachs
7 views
mSWI/SNF complex inhibition sensitizes KRAS-mutant lung cancers to targeted therapies via epithelial-mesenchymal subversion

mSWI/SNF complex inhibition sensitizes KRAS-mu...

Cancer Biology
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Cigall Kadoch
12 views
Pancreatic cancer-associated organ dysfunction promotes muscle autophagy and contributes to peripheral tissue wasting

Pancreatic cancer-associated organ dysfunction...

Cancer Biology
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librarian
10 views
Spatially Integrated Multi-Omics reveals the Multicellular Landscape of Progenitor-Driven Glioblastoma Progression

Spatially Integrated Multi-Omics reveals the M...

Cancer Biology
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librarian
22 views
Next-generation all-in-one CRISPR/Cas9 multiply-edited CD30CAR-T cells:Potency despite risk of translocations

Next-generation all-in-one CRISPR/Cas9 multipl...

Cancer Biology
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librarian
13 views
A Comparison of Mechanisms Driving Lesion Outcomes during Lung Tumor and Tuberculosis Granuloma Formation

A Comparison of Mechanisms Driving Lesion Outc...

Cancer Biology
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librarian
11 views
Identifying Robust Subclonal Structures through Tumor Progression Tree Alignment

Identifying Robust Subclonal Structures throug...

Cancer Biology
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librarian
11 views
Anti-diabetic drug Repaglinide induces Apoptosis, Cell Cycle Arrest, and Inhibits Cell Migration in Human Breast and Lung Cancer Cells.

Anti-diabetic drug Repaglinide induces Apoptos...

Cancer Biology
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Govinda Rao Duddukuri
11 views
The vitamin K oxidoreductase VKORC1L1 prevents oxidative stress in hepatocytes and protects from MASLD and hepatocellular carcinoma

The vitamin K oxidoreductase VKORC1L1 prevents...

Cancer Biology
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Mathieu Ferron
13 views
Assessing the Operational Feasibility of Evolutionary Therapy in Metastatic Non-Small Cell Lung Cancer

Assessing the Operational Feasibility of Evolu...

Cancer Biology
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librarian
7 views
CKII-Phosphorylated HPV-16 E7 Disrupts Planar Cell Polarity by Recruiting Vangl1

CKII-Phosphorylated HPV-16 E7 Disrupts Planar ...

Cancer Biology
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Ifeoluwa Gbala
9 views
Inhibition of mucin-type O-glycosylation impairs melanogenesis, melanoma growth, and metastatic capacity

Inhibition of mucin-type O-glycosylation impai...

Cancer Biology
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Srinivasa-Gopalan Sampathkumar
27 views
Dissecting FOXA1 pioneering function by acute pharmacological degradation

Dissecting FOXA1 pioneering function by acute ...

Cancer Biology
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librarian
11 views
Domain-adaptation deep learning models do not outperform simple baseline models in single-cell anti-cancer drug sensitivity prediction

Domain-adaptation deep learning models do not ...

Cancer Biology
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Marina Esteban-Medina
14 views
Iron Metabolism as a Therapeutic Vulnerability in Stem Cell-Like Castration-Resistant Prostate Cancer

Iron Metabolism as a Therapeutic Vulnerability...

Cancer Biology
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librarian
16 views
Pharmacological targeting of EED is an effective therapeutic strategy in cellular models of incurable neuroendocrine prostate cancer

Pharmacological targeting of EED is an effecti...

Cancer Biology
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Kayleigh Orchard
12 views
Leukemia stem cell expansion cultures reveal clonal drivers of leukemogenesis and therapy response

Leukemia stem cell expansion cultures reveal c...

Cancer Biology
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librarian
10 views
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