Bioinformatics

Horse, not zebra: accounting for lineage abundance in maximum likelihood phylogenetics

Horse, not zebra: accounting for lineage abund...

Bioinformatics
Avatar
librarian
0 views
GYDE: A collaborative drug discovery platform for AI-powered protein design and engineering

GYDE: A collaborative drug discovery platform ...

Bioinformatics
Avatar
librarian
0 views
MEIsensor: a deep-learning method for mobile element insertion discovery

MEIsensor: a deep-learning method for mobile e...

Bioinformatics
Avatar
librarian
3 views
Why phylogenies compress so well: combinatorial guarantees under the Infinite Sites Model

Why phylogenies compress so well: combinatoria...

Bioinformatics
Avatar
librarian
2 views
DynaBiomeX: An Interpretable Dual-Strategy Deep Learning Framework for Architectural Noise Filtration in Sparse Longitudinal Microbiome Data

DynaBiomeX: An Interpretable Dual-Strategy Dee...

Bioinformatics
Avatar
Awais Qureshi
6 views
GraphHDBSCAN*: Graph-based Hierarchical Clustering on High Dimensional Single-cell RNA Sequencing Data

GraphHDBSCAN*: Graph-based Hierarchical Cluste...

Bioinformatics
Avatar
Seyed Ardalan Ghoreishi
2 views
Self-supervised learning for a gene program-centric view of cell states

Self-supervised learning for a gene program-ce...

Bioinformatics
Avatar
librarian
2 views
Is metabolism spatially optimized? Structural modeling of consecutive enzyme pairs reveals no evidence for spatial optimization of catalytic site proximity.

Is metabolism spatially optimized? Structural ...

Bioinformatics
Avatar
librarian
1 view
Emergent Biological Realism in RL-Trained DNA Language Models

Emergent Biological Realism in RL-Trained DNA ...

Bioinformatics
Avatar
librarian
2 views
Nextstrain automates real-time phylodynamic analysis of open data for endemic and emerging pathogens

Nextstrain automates real-time phylodynamic an...

Bioinformatics
Avatar
librarian
1 view
Scaling and Generalization of Discrete Diffusion Models for Tumor Phylogenies

Scaling and Generalization of Discrete Diffusi...

Bioinformatics
Avatar
Siddharth Sabata
1 view
FoundedPBI: Using Genomic Foundation Models to predict Phage-Bacterium Interactions

FoundedPBI: Using Genomic Foundation Models to...

Bioinformatics
Avatar
librarian
1 view
Experimental mismatch in benchmarking PELSA and LiP-MS

Experimental mismatch in benchmarking PELSA an...

Bioinformatics
Avatar
librarian
11 views
Predicting Unseen Gene Perturbation Response Using Graph Neural Networks with Biological Priors

Predicting Unseen Gene Perturbation Response U...

Bioinformatics
Avatar
librarian
1 view
skDER: microbial genome dereplication approaches for comparative and metagenomic applications

skDER: microbial genome dereplication approach...

Bioinformatics
Avatar
Rauf Salamzade
2 views
Single-cell Transcriptomic Variance Analysis Reveals Intercellular Circadian Desynchrony in the Alzheimer's Affected Human Brain

Single-cell Transcriptomic Variance Analysis R...

Bioinformatics
Avatar
Ron Anafi
4 views
Thirty years of Achromobacter ruhlandii evolution reveal pathways to epidemic lineages

Thirty years of Achromobacter ruhlandii evolut...

Bioinformatics
Avatar
librarian
3 views
Population-scale interpretation of RNA isoform diversity enabled by Isopedia

Population-scale interpretation of RNA isoform...

Bioinformatics
Avatar
librarian
4 views
Compact longitudinal representations derived from mixed-format lifestyle questionnaires outperform static text-derived features for ALS-versus-control classification

Compact longitudinal representations derived f...

Bioinformatics
Avatar
librarian
3 views
Computational Design and Atomistic Validation of a High-Affinity VHH Nanobody Targeting the PI/RuvC Interface of Streptococcus pyogenes Cas9: A Bivalent Hub Strategy for CRISPR-Cas9 Enhancement

Computational Design and Atomistic Validation ...

Bioinformatics
Avatar
librarian
4 views
AI-guided design of candidate BMPR1A-binding peptides for cartilage regeneration: a multi-tool computational benchmarking study

AI-guided design of candidate BMPR1A-binding p...

Bioinformatics
Avatar
librarian
4 views
STRmie-HD enables interruption-aware HTT repeat genotyping and somatic mosaicism profiling across sequencing platforms

STRmie-HD enables interruption-aware HTT repea...

Bioinformatics
Avatar
Alessandro Napoli
4 views
From SNPs to Pathways: A genome-wide benchmark of annotation discrepancies and their impact on protein- and pathway-level inference

From SNPs to Pathways: A genome-wide benchmark...

Bioinformatics
Avatar
librarian
3 views
dreampy: Pseudobulk mixed-model differential expression for single-cell RNA-seq in Python

dreampy: Pseudobulk mixed-model differential e...

Bioinformatics
Avatar
librarian
5 views
PACMON: Pathway-guided Multi-Omics data integration for interpreting large-scale perturbation screens

PACMON: Pathway-guided Multi-Omics data integr...

Bioinformatics
Avatar
Florian Buettner
1 view
MiCBuS: Marker Gene Mining for Unknown Cell Types Using Bulk and Single Cell RNA-Seq Data

MiCBuS: Marker Gene Mining for Unknown Cell Ty...

Bioinformatics
Avatar
Shanshan Zhang
1 view
Col-Ovo: Smartphone-based artificial intelligence for rapid counting of Aedes mosquito eggs under field conditions

Col-Ovo: Smartphone-based artificial intellige...

Bioinformatics
Avatar
Diego Montenegro
4 views
A comprehensive reference database to support untargeted metabolomics in Pseuudomonas putida

A comprehensive reference database to support ...

Bioinformatics
Avatar
Jessica Bade
5 views
VPF-Class 2.0: a taxonomy-centered framework for automatic viral classification

VPF-Class 2.0: a taxonomy-centered framework f...

Bioinformatics
Avatar
librarian
10 views
Single-cell Landscape of T Cell Heterogeneity in Kawasaki Disease: STAT3/JAK Axis Regulates the Lineage Differentiation Bias of Th17 Cells

Single-cell Landscape of T Cell Heterogeneity ...

Bioinformatics
Avatar
Sirui Song
9 views
TogoMCP: Natural Language Querying of Life-Science Knowledge Graphs via Schema-Guided LLMs and the Model Context Protocol

TogoMCP: Natural Language Querying of Life-Sci...

Bioinformatics
Avatar
librarian
10 views
Rastair: an integrated variant and methylation caller

Rastair: an integrated variant and methylation...

Bioinformatics
Avatar
Benjamin Schuster-Boeckler
12 views
Load more